Citicoline: A Useful Supplement For Medical Cannabis Patients
Cannabis oil, even when made from high CBD content cannabis strains is also high in THC and for many cancer patients that have not consumed cannabis before and therefore have a low tolerance to THC’s psychoactivity on the brain this can be an unpleasant side effect, similarly this can be a problem when children are prescribed medical marijuana.
There is, however, a supplement that can be ordered online called Citicoline available in 250 or 500 mg – taken an hour before cannabis is ingested, be it oil or herbal based treatments, it greatly reduces THC’s psychoactive effect.
It is available on prescription in many European countries, however,Citicoline is also marketed as a dietary supplement, despite being originally developed in Japan to help stroke victims. Citicoline is available online and in stores in over 70 countries under a variety of brand names such as Ceraxon, Cognizin, NeurAxon and Somazina.
Citicoline is a brain chemical that occurs naturally in the body and increases a chemical called phosphatidylcholine that is important for brain function.
A 10% loss of citicoline is sufficient to alter brain cell membrane function and induce neuron cell death.
When taken as a supplement Citicoline is hydrolyzed into choline and cytidine in the intestine.
Once these cross the blood-brain barrier it is reformed into citicoline.
As a medicine, it is taken as a supplement, given by IV or as an injection to treat dementia, head trauma, cerebrovascular disease such as stroke, age-related memory loss, Parkinson’s disease, ADHD and glaucoma.
The U.S. National Institute on Drug Abuse (NIDA) has recognized the value of the supplement in reducing the effect Of THC and been carrying out trials on Citacoline, however, the basis of these trials is to determine if the chemical will help to ‘cure’ individuals whom they claim are cannabis dependent.
They issued a participation request in November 2012 (ID: NCT00158249) asking for volunteers and defined ‘heavy’ cannabis users as individuals who smoked 10 cannabis cigarettes (joints) a week.
The fact is that cannabis does not cause dependence and this has been proven in numerous clinical trials, there is the possibility that chronic users can develop a psychological need for the effects of cannabis smoking, however, there are only minor withdrawal symptoms when marijuana use is discontinued.
Consuming 10 cannabis joints a week is not heavy use and cynics would argue that these trials are conceived by pharmaceutical lobbyists to continue the misinformation required to deny cannabis as a freely available medicine.
Citicolene is not toxic, although it can upset some peoples stomachs if large doses are taken. It is advisable to self-titrate, i.e. start with a small dose of 250 mg and increase the dose slowly until the desired effect is achieved. A single dose of Citicolene taken one hour before ingesting cannabis oil should be sufficient to allow users who have not built up a tolerance to THC to comfortably take their anti cancer treatment without any side effects.
The most effective oral dosages for cannabis users is between 250 and 500 mg taken one hour before treatment. This is a low dosage when you consider many stroke and Alzheimers patients can take up to 2,000 mg.
Citicoline has a very low toxicity profile in animals and humans. Clinically, doses of 2000 mg per day have been observed and approved. Minor adverse effects most commonly include stomach pain and diarrhea.